Le Journal

Pfizer’s recent bidding war for an obesity biotech clearly hasn’t satiated the pharma’s appetite for new GLP-1 therapies—at least going by this morning’s $1.9 billion biobucks deal.

The medical device manufacturing and distribution giant could claim a valuation of about $55 billion if it reaches the top of its range.

It wasn’t all that long ago that a Packers team with Super Bowl aspirations faced a Denver Broncos team with an elite defense. The year was 2015. Despite the preseason loss of Jordy Nelson, the Packers opened the season with a sprint to a 6-0 start, putting up at least 27 points in four of those six wins. Then they had a bye. Then the Broncos took them apart. Boasting a truly great defense, the Broncos solved the Packers’ offense completely, and in doing so showed the rest of the league how they could be beaten. By the end of November, the Packers were 7-4 and had to scratch and claw to make it to 10-6 on the year. It’s overly reductionist to say that the Broncos really ruined the Packers that thoroughly. There were plenty of other factors in the Packers’ decline. Nelson’s absence was significant, and elsewhere in the receiving corps, Randall Cobb and second-year man Davante Adams were both banged up as well. Running back Eddie Lacy was similarly nicked up (in addition to struggling with weight issues), and only one player on the offensive line started all 16 games. But the Broncos certainly didn’t help, and it’s not a stretch to say they played a big role in ruining the Packers’ season. There is a very clear “before Denver” and “after Denver” demarcation in the 2015 Packers’ season. This year’s Packers team is not without its issues, but it seems better positioned to handle a blitz from Denver than the 2015 unit. Still, it’s hard to forget how big of an impact a single game can have, and with a narrow margin for error, the Packers would be wise to remember the lessons of 2015. Facing Broncos’ vaunted defense, Packers ‘know what we’ve got’ | Packers.com The story of the Denver Broncos is their defense, and the Packers are well aware. This is what makes Packers safety Evan Williams so special | Packer News The Packers have plenty to talk about on their own defense, including safety Evan Williams. Former Strength of Packers Could Return, Just in Time for Broncos | Sports Illustrated The absent strength has been yards after the catch, but Christian Watson’s emergence has brought that back to an extent. Packers rookie report Week 14: Anthony Belton plays best game yet vs. Bears | Packers Wire Speaking of strength, Anthony Belton has shown plenty of it during his work as a starting lineman for the Packers. Ranking NFL MVP candidates: Matthew Stafford vs. Drake Maye | ESPN Jordan Love comes out looking pretty good in this conversation. Hiker mired in quicksand in Utah’s Arches National Park is rescued unharmed | Associated Press I’m far from the first to make this kind of joke, but I was led to believe that quicksand was going to be a much bigger issue than it turned out to be. But then there’s this guy!

The Green Bay Packers had one lone non-participant in Wednesday’s practice: running back Josh Jacobs, who was given a knee designation. This isn’t too uncommon for Jacobs, who hurt his knee against the New York Giants, but it is a situation to monitor throughout the week. If I were to guess, Jacobs will play against the Denver Broncos, despite being on the injury report, like he has the last two weeks. Beyond Jacobs, though, receiver Savion Williams (foot) and defensive end Lukas Van Ness (foot), who missed last week’s game against the Chicago Bears, were both limited participants in practice on Wednesday. That’s a positive sign for their injury outlooks. The Packers particularly need Van Ness back, as the team got little to no pass-rush push from the interior defensive line following Devonte Wyatt’s season-ending injury. Generally, Green Bay seemed pretty conservative from an injury perspective today, which is interesting. On one hand, the team is going to elevation in Denver this week and probably needs to be well-conditioned for the environment. On the other hand, you also don’t want to wear out players before playing at Mile High. Green Bay Packers Limited Participants RB MarShawn Lloyd (calf, IR) WR Jayden Reed (shoulder) WR Dontayvion Wicks (ankle) WR Matthew Golden (wrist) WR Savion Williams (foot) RT Zach Tom (back) DE Lukas Van Ness (foot) DE Kingsley Enagbare (knee) DE Collin Oliver (hamstring, PUP) DE Brenton Cox Jr. (groin, IR) DT Jordon Riley (knee) LB Kristian Welch (concussion) S Javon Bullard (ankle) The Packers have another week to decide whether to call up running back MarShawn Lloyd (IR), defensive end Collin Oliver (PUP) or defensive end Brenton Cox Jr. (IR) to the 53-man roster. If they don’t do that next week, then the players will revert to the injury lists for the remainder of the 2025 season. Beyond Van Ness and Williams, who we’ve already touched on, the only other player on the list who was unable to finish the game against the Bears last week was linebacker Kristian Welch, who dropped out with a concussion. Receivers Dontayvion Wicks and Matthew Golden didn’t play much against Chicago due to injury, but the team never gave them in-game injury statuses. Denver Broncos Injuries WR Pat Bryant (hamstring, DNP) TE Nate Adkins (knee, limited) OL Ben Powers (biceps, IR, limited) The only real major injury that the Broncos are dealing with right now is the hamstring of Pat Bryant, who is arguably the team’s number-two receiver. Bryant has posted 199 receiving yards in his last four games with Denver, including four receptions for 32 yards against the Las Vegas Raiders last week. Josh Jacobs still listed as just a knee issue on the injury report. Full injury report below. pic.twitter.com/tqSpj93ITp— Eric Boynton (@ericboynton) December 10, 2025

The NFL announced on Wednesday that the Green Bay Packers’ Week 17 game against the Baltimore Ravens has been scheduled for Saturday, December 27th at 7 pm CT. Previously, the game was scheduled as “TBD,” but now the game is officially the second part of a Saturday doubleheader with the Houston Texans and Los Angeles Chargers playing at 3:30 pm CT on NFL Network. Packers vs. Ravens will be played exclusively on the Peacock streaming service, outside of the local Packers footprint. This should give Green Bay a little extra rest going into their season finale against the Minnesota Vikings, who will be playing on Christmas Day before their matchup. The Week 18 game’s kickoff time has yet to be announced, but it can be played on either January 3rd or 4th. So, yes, with the Bears and Ravens games falling on a Saturday and Saturday being an option for the Vikings game, the Packers might end the season with three straight Saturday kickoffs. Welcome to the NFL in 2025. Depending on how the playoffs shake out, last week’s win over the Bears could have been the last Sunday game at Lambeau Field this season. If you want to make it to the Packers’ regular-season home finale, you’re going to have to make plans for Saturday.