Le Journal

Medicare premiums to jump 10% heading into 2026

Five Free Agents the Mets Should Target This Winter

STAT+: Pfizer closes $10 billion Metsera deal

Judge says he’ll approve opioid settlement with OxyContin maker Purdue and Sackler family

Opinion: Celebrating a new, faster path to gene-editing medicines on demand
In May, news broke of a biomedical first: the on-demand design and clinical use of a personalized gene editor for a baby boy born with a rare, severe genetic condition. At the STAT Summit in October, the child’s treating physician from the Children’s Hospital of Philadelphia (CHOP) and the lead on developing the gene editor for him shared the stage with him and his parents. The video of a happily squirming 1-year-old brought tears of joy to the eyes of many. A sobering reminder of the long road ahead toward more such videos was shared in these pages by Celena Lozano, whose son lives with a no less rare and severe genetic condition called PURA syndrome. Concerned over false hope inadvertently created by exuberant media coverage of the success story, she wrote, “families of the rare disease community deserve to have a better understanding of when their child might be next.”Read the rest…

Advocates decry intersex exceptions in trans health bans

STAT+: Up and down the ladder: The latest comings and goings

Comment on The Drab Five: A Look at the 5 Biggest Mistakes of the Raiders’ Offseason by Raiderro
Although the Darnold situation is still the worse, I must say the failure to resign Chaisson is up there too. Dude had a great year under Leonard, our best coach, and he could’ve been had for peanuts

Comment on Raiders Insider Raises Interesting Speculation on Patrick Graham’s Future in Las Vegas by Raiderro

NIH abruptly places outspoken critic of Trump administration on leave

STAT+: Pharmalittle: We’re reading about a Merck acquisition, Novo facing shareholder backlash, and more

